Lyon Perrache (XYL) is a railway station in central Lyon, France, not an airport, so the honest answer to does Lyon Perrache have a lounge is no: there is no commercial airport at this station to operate one. Lyon Perrache itself sits within walking distance of Lyon's Presqu'ile old town and the Confluence district, a fitting stop for sightseeing before an onward journey rather than a departure point in its own right. The actual lounge picture for Lyon-area travellers belongs to Lyon-Saint Exupery Airport (LYS), the city's air gateway, reached from Perrache by tram, rail link, or a short taxi ride.
Lyon-Saint Exupery, as the primary airport serving France's third-largest metropolitan area, supports a lounge picture built around airline lounges for premium-cabin and elite-status passengers, plus Priority Pass and credit-card network coverage typical of a mid-size European hub with a mix of domestic, European, and some longer-haul routes. It is smaller than Paris's major hubs, so expect a more modest spread of lounges than you would find at Charles de Gaulle, but a genuine airport lounge picture nonetheless.
Exactly which lounges operate, their hours, and which memberships or cards they accept can shift with airline schedule changes and terminal updates, so confirm current details directly with Lyon-Saint Exupery, your airline, or your card issuer before you fly rather than relying on general assumptions carried over from a larger hub.
For most travellers passing through Lyon Perrache on their way to catch a flight, the practical plan is straightforward: the station itself has no lounge to offer, but Lyon-Saint Exupery Airport does maintain real lounge access worth checking against your specific fare, status, or membership. Budget extra time for the tram or rail transfer between Perrache and Lyon-Saint Exupery, particularly during peak commuter hours in central Lyon. Verify the current picture for LYS before you build a lounge stop into your travel plans.